134B29 specifically recognizes the C-terminal RGDS containing sequence of the fibrinogen α chain, but not others RGDS sequence in fibrinogen itself, nor other adhesive molecules, such as von Willeband Factor (vWF), for which clone 152B6 should be used. This antibody is a functional blocking mAb; it inhibits the interaction between C-terminal RGDS sequence of fibrinogen and the human endothelial cell receptor integrin αVβ3. Available unlabeled and labeled.
Clone & Isotope