In Vitro

  • Real-time binding kinetics of mAbs or ligand interaction with platelet receptors
  • Characterization of antiplatelet drug inhibitory potential by agonist-induced aggregation
  • Coming soon: Shear-induced aggregation

Ex Vivo

  • Design, execution, and interpretation of thrombogenesis studies under selected flow conditions, with visualization of platelets, platelet aggregates and fibrin deposition

In Vivo

  • Ferric chloride (FeCl3)- or laser-induced models of arterial and venous thrombosis
  • Unique, humanized animal models
    » Human GPIbα/human VWF A1 domain interaction
    » Coming soon: Thrombin/human hPAR1 interaction